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The metabolomic profile of gamma-irradiated human hepatoma and muscle cells reveals metabolic changes consistent with the Warburg effect

The two human cell lines HepG2 from hepatoma and HMCL-7304 from striated muscle were γ-irradiated with doses between 0 and 4 Gy. Abundant γH2AX foci were observed at 4 Gy after 4 h of culture post-irradiation. Sham-irradiated cells showed no γH2AX foci and therefore no signs of radiation-induced dou...

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Vydáno v:PeerJ
Hlavní autoři: Wang, Min, Keogh, Adrian, Treves, Susan, Idle, Jeffrey R., Beyoğlu, Diren
Médium: Artigo
Jazyk:Inglês
Vydáno: PeerJ Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730869/
https://ncbi.nlm.nih.gov/pubmed/26823999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.1624
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