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Characterization of a novel adult murine immortalized microglial cell line and its activation by amyloid-beta
BACKGROUND: Alzheimer’s disease is associated with amyloid-beta (Aβ)-induced microglia activation. This pro-inflammatory response promotes neuronal damage, and therapies are sought to limit microglial activation. Screening efforts to develop new pharmacological inhibitors require a robust in vitro c...
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| Publicado no: | J Neuroinflammation |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4730646/ https://ncbi.nlm.nih.gov/pubmed/26819091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0484-z |
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