The cardiovascular and hypothalamus-pituitary-adrenal axis response to stress is controlled by glucocorticoid receptor sequence variants and promoter methylation

BACKGROUND: Gender, genetic makeup, and prior experience interact to determine physiological responses to an external perceived stressor. Here, we investigated the contribution of both genetic variants and promoter methylation of the NR3C1 (glucocorticoid receptor) gene to the cardiovascular and hyp...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Li-Tempel, Ting, Larra, Mauro F., Sandt, Estelle, Mériaux, Sophie B., Schote, Andrea B., Schächinger, Hartmut, Muller, Claude P., Turner, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730588/
https://ncbi.nlm.nih.gov/pubmed/26823689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0180-y
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