Neutralization of Clostridium difficile Toxin B Mediated by Engineered Lactobacilli That Produce Single-Domain Antibodies

Clostridium difficile is the primary cause of nosocomial antibiotic-associated diarrhea in the Western world. The major virulence factors of C. difficile are two exotoxins, toxin A (TcdA) and toxin B (TcdB), which cause extensive colonic inflammation and epithelial damage manifested by episodes of d...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Infect Immun
Hlavní autoři: Andersen, Kasper Krogh, Strokappe, Nika M., Hultberg, Anna, Truusalu, Kai, Smidt, Imbi, Mikelsaar, Raik-Hiio, Mikelsaar, Marika, Verrips, Theo, Hammarström, Lennart, Marcotte, Harold
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730582/
https://ncbi.nlm.nih.gov/pubmed/26573738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00870-15
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky