Wird geladen...
Metformin Restores Parkin-Mediated Mitophagy, Suppressed by Cytosolic p53
Metformin is known to alleviate hepatosteatosis by inducing 5’ adenosine monophosphate (AMP)-kinase-independent, sirtuin 1 (SIRT1)-mediated autophagy. Dysfunctional mitophagy in response to glucolipotoxicities might play an important role in hepatosteatosis. Here, we investigated the mechanism by wh...
Gespeichert in:
| Veröffentlicht in: | Int J Mol Sci |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2016
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4730363/ https://ncbi.nlm.nih.gov/pubmed/26784190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17010122 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|