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Transactivation of Epidermal Growth Factor Receptor by G Protein-Coupled Receptors: Recent Progress, Challenges and Future Research

Both G protein-coupled receptors (GPCRs) and receptor-tyrosine kinases (RTKs) regulate large signaling networks, control multiple cell functions and are implicated in many diseases including various cancers. Both of them are also the top therapeutic targets for disease treatment. The discovery of th...

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Vydáno v:Int J Mol Sci
Hlavní autor: Wang, Zhixiang
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730337/
https://ncbi.nlm.nih.gov/pubmed/26771606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17010095
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