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Aire-Overexpressing Dendritic Cells Induce Peripheral CD4(+) T Cell Tolerance
Autoimmune regulator (Aire) can promote the ectopic expression of peripheral tissue-restricted antigens (TRAs) in thymic medullary epithelial cells (mTECs), which leads to the deletion of autoreactive T cells and consequently prevents autoimmune diseases. However, the functions of Aire in the periph...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4730283/ https://ncbi.nlm.nih.gov/pubmed/26729097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17010038 |
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