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Evidence for opioid modulation and generation of prostaglandins in sulphur dioxide (SO)2-induced bronchoconstriction.

BACKGROUND: Inhalation of sulphur dioxide (SO2) provokes bronchoconstriction in asthmatic subjects. Cholinergic mechanisms contribute, but other mechanisms remain undefined. The effect of morphine, an opioid agonist, on the cholinergic component of SO2-induced bronchoconstriction was investigated, a...

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Published in:Thorax
Main Authors: Field, P. I., Simmul, R., Bell, S. C., Allen, D. H., Berend, N.
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 1996
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC473026/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8711648/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/thx.51.2.159
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