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X-ray induced singlet oxygen generation by nanoparticle-photosensitizer conjugates for photodynamic therapy: determination of singlet oxygen quantum yield

Singlet oxygen is a primary cytotoxic agent in photodynamic therapy. We show that CeF(3) nanoparticles, pure as well as conjugated through electrostatic interaction with the photosensitizer verteporfin, are able to generate singlet oxygen as a result of UV light and 8 keV X-ray irradiation. The X-ra...

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Pubblicato in:Sci Rep
Autori principali: Clement, Sandhya, Deng, Wei, Camilleri, Elizabeth, Wilson, Brian C., Goldys, Ewa M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730142/
https://ncbi.nlm.nih.gov/pubmed/26818819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19954
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