Low cytoplasmic and nuclear KPNA2 expression in radiotherapy-treated head and neck squamous cell cancer is associated with an adverse outcome

Background: KPNA2 has effects on carcinogenesis, cell differentiation and transcriptional regulation. KPNA2 has been linked to DNA damage repair by its role to import the DNA double strand break repair complex MRN into the nucleus. The aim of our study was to evaluate the prognostic value of KPNA2 e...

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Vydáno v:Int J Clin Exp Pathol
Hlavní autoři: Erben, Pia B, Brunner, Kathrin, Hecht, Markus, Haderlein, Marlen, Büttner-Herold, Maike, Agaimy, Abbas, Fietkau, Rainer, Hartmann, Arndt, Distel, Luitpold V
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2015
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730065/
https://ncbi.nlm.nih.gov/pubmed/26884852
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