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Human pancreatic beta-like cells converted from fibroblasts

Pancreatic beta cells are of great interest for biomedical research and regenerative medicine. Here we show the conversion of human fibroblasts towards an endodermal cell fate by employing non-integrative episomal reprogramming factors in combination with specific growth factors and chemical compoun...

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Publicat a:Nat Commun
Autors principals: Zhu, Saiyong, Russ, Holger A., Wang, Xiaojing, Zhang, Mingliang, Ma, Tianhua, Xu, Tao, Tang, Shibing, Hebrok, Matthias, Ding, Sheng
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729817/
https://ncbi.nlm.nih.gov/pubmed/26733021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10080
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