BET Bromodomain Inhibition as a Therapeutic Strategy in Ovarian Cancer by Downregulating FoxM1

Ovarian cancer is responsible for the highest mortality among all gynecologic malignancies, and novel therapies are urgently needed to improve patient outcome. Here we performed an integrative genomic analysis and identified the bromodomain and extraterminal domain (BET) protein BRD4 as a potential...

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Detalles Bibliográficos
Publicado en:Theranostics
Main Authors: Zhang, Zhenfeng, Ma, Pengfei, Jing, Ying, Yan, Ying, Cai, Mei-Chun, Zhang, Meiying, Zhang, Shengzhe, Peng, Huixin, Ji, Zhi-Liang, Di, Wen, Gu, Zhenyu, Gao, Wei-Qiang, Zhuang, Guanglei
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729770/
https://ncbi.nlm.nih.gov/pubmed/26877780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.13178
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