BET Bromodomain Inhibition as a Therapeutic Strategy in Ovarian Cancer by Downregulating FoxM1

Ovarian cancer is responsible for the highest mortality among all gynecologic malignancies, and novel therapies are urgently needed to improve patient outcome. Here we performed an integrative genomic analysis and identified the bromodomain and extraterminal domain (BET) protein BRD4 as a potential...

詳細記述

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書誌詳細
出版年:Theranostics
主要な著者: Zhang, Zhenfeng, Ma, Pengfei, Jing, Ying, Yan, Ying, Cai, Mei-Chun, Zhang, Meiying, Zhang, Shengzhe, Peng, Huixin, Ji, Zhi-Liang, Di, Wen, Gu, Zhenyu, Gao, Wei-Qiang, Zhuang, Guanglei
フォーマット: Artigo
言語:Inglês
出版事項: Ivyspring International Publisher 2016
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729770/
https://ncbi.nlm.nih.gov/pubmed/26877780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.13178
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