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Binding Site Identification and Flexible Docking of Single Stranded RNA to Proteins Using a Fragment-Based Approach

Protein-RNA docking is hampered by the high flexibility of RNA, and particularly single-stranded RNA (ssRNA). Yet, ssRNA regions typically carry the specificity of protein recognition. The lack of methodology for modeling such regions limits the accuracy of current protein-RNA docking methods. We de...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Chauvot de Beauchene, Isaure, de Vries, Sjoerd J., Zacharias, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729675/
https://ncbi.nlm.nih.gov/pubmed/26815409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004697
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