Genome-wide association analysis of young onset stroke identifies a locus on chromosome 10q25 near HABP2

BACKGROUND AND PURPOSE: Although a genetic contribution to ischemic stroke is well recognized, only a handful of stroke loci have been identified by large-scale genetic association studies to date. Hypothesizing that genetic effects might be stronger for early- versus late-onset stroke, we conducted...

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Publicado no:Stroke
Main Authors: Cheng, Yu-Ching, Stanne, Tara M., Giese, Anne-Katrin, Ho, Weang Kee, Traylor, Matthew, Amouyel, Philippe, Holliday, Elizabeth G., Malik, Rainer, Xu, Huichun, Kittner, Steven J., Cole, John W., O’Connell, Jeffrey R., Danesh, John, Rasheed, Asif, Zhao, Wei, Engelter, Stefan, Grond-Ginsbach, Caspar, Kamatani, Yoichiro, Lathrop, Mark, Leys, Didier, Thijs, Vincent, Metso, Tiina M., Tatlisumak, Turgut, Pezzini, Alessandro, Parati, Eugenio A., Norrving, Bo, Bevan, Steve, Rothwell, Peter M, Sudlow, Cathie, Slowik, Agnieszka, Lindgren, Arne, Walters, Matthew R, Jannes, Jim, Shen, Jess, Crosslin, David, Doheny, Kimberly, Laurie, Cathy C., Kanse, Sandip M., Bis, Joshua C., Fornage, Myriam, Mosley, Thomas H., Hopewell, Jemma C., Strauch, Konstantin, Müller-Nurasyid, Martina, Gieger, Christian, Waldenberger, Melanie, Peters, Annette, Meisinger, Christine, Ikram, M. Arfan, Longstreth, WT, Meschia, James F., Seshadri, Sudha, Sharma, Pankaj, Worrall, Bradford, Jern, Christina, Levi, Christopher, Dichgans, Martin, Boncoraglio, Giorgio B., Markus, Hugh S., Debette, Stephanie, Rolfs, Arndt, Saleheen, Danish, Mitchell, Braxton D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729659/
https://ncbi.nlm.nih.gov/pubmed/26732560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.115.011328
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