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Isoproterenol Promotes Rapid Ryanodine Receptor Movement to BIN1 Organized Dyads
BACKGROUND: The key pathophysiology of human acquired heart failure is impaired calcium transient, which is initiated at dyads consisting ryanodine receptors (RyR) at sarcoplasmic reticulum apposing Ca(V)1.2 channels at t-tubules. Sympathetic tone regulates myocardial calcium transients through β-ad...
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| Udgivet i: | Circulation |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4729615/ https://ncbi.nlm.nih.gov/pubmed/26733606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.018535 |
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