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Interleukin-4 is Essential for Microglia/Macrophage M2 Polarization and Long-term Recovery after Cerebral Ischemia

BACKGROUND AND PURPOSE: Interleukin-4 (IL-4) is a unique cytokine that may contribute to brain repair by regulating microglia/macrophage functions. Thus, we examined the effect of IL-4 on long-term recovery and microglia/macrophage polarization in two well-established stroke models. METHODS: Transie...

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Bibliographische Detailangaben
Veröffentlicht in:Stroke
Hauptverfasser: Liu, Xiangrong, Liu, Jia, Zhao, Shangfeng, Zhang, Haiyue, Cai, Wei, Cai, Mengfei, Ji, Xunming, Leak, Rehana K., Gao, Yanqin, Chen, Jun, Hu, Xiaoming
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729613/
https://ncbi.nlm.nih.gov/pubmed/26732561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.115.012079
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