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Purification and characterization of tenerplasminin-1, a serine peptidase inhibitor with antiplasmin activity from the coral snake (Micrurus tener tener) venom

A plasmin inhibitor, named tenerplasminin-1 (TP1), was isolated from Micrurus tener tener (Mtt) venom. It showed a molecular mass of 6542 Da, similarly to Kunitz-type serine peptidase inhibitors. The amidolytic activity of plasmin (0.5 nM) on synthetic substrate S-2251 was inhibited by 91% following...

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Detalhes bibliográficos
Publicado no:Comp Biochem Physiol C Toxicol Pharmacol
Main Authors: Vivas, Jeilyn, Ibarra, Carlos, Salazar, Ana M., Neves-Ferreira, Ana G.C., Sánchez, Elda E., Perales, Jonás, Rodríguez-Acosta, Alexis, Guerrero, Belsy
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729579/
https://ncbi.nlm.nih.gov/pubmed/26419785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpc.2015.09.009
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