Effects of eltrombopag on platelet count and platelet activation in Wiskott-Aldrich syndrome/X-linked thrombocytopenia

Because Wiskott-Aldrich syndrome (WAS) and X-linked thrombocytopenia (XLT) patients have microthrombocytopenia, hemorrhage is a major problem. We asked whether eltrombopag, a thrombopoietic agent, would increase platelet counts, improve platelet activation, and/or reduce bleeding in WAS/XLT patients...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Gerrits, Anja J., Leven, Emily A., Frelinger, Andrew L., Brigstocke, Sophie L., Berny-Lang, Michelle A., Mitchell, W. Beau, Revel-Vilk, Shoshana, Tamary, Hannah, Carmichael, Sabrina L., Barnard, Marc R., Michelson, Alan D., Bussel, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729539/
https://ncbi.nlm.nih.gov/pubmed/26224646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-09-602573
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