Type 1 diabetes immunotherapy using polyclonal regulatory T cells

Type 1 diabetes (T1D) is an autoimmune disease that occurs in genetically susceptible individuals. Regulatory T cells (Tregs) have been shown to be defective in the autoimmune disease setting. Thus, efforts to repair or replace Tregs in T1D may reverse autoimmunity and protect the remaining insulin-...

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Bibliografiska uppgifter
I publikationen:Sci Transl Med
Huvudupphovsmän: Bluestone, Jeffrey A., Buckner, Jane H., Fitch, Mark, Gitelman, Stephen E., Gupta, Shipra, Hellerstein, Marc K., Herold, Kevan C., Lares, Angela, Lee, Michael R., Li, Kevin, Liu, Weihong, Long, S. Alice, Masiello, Lisa M., Nguyen, Vinh, Putnam, Amy L., Rieck, Mary, Sayre, Peter, Tang, Qizhi
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729454/
https://ncbi.nlm.nih.gov/pubmed/26606968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aad4134
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