Haloarchaeal gas vesicle nanoparticles displaying Salmonella SopB antigen reduce bacterial burden when administered with live attenuated bacteria

Innovative vaccines against typhoid and other Salmonella diseases that are safe, effective, and inexpensive are urgently needed. In order to address this need, buoyant, self-adjuvating gas vesicle nanoparticles (GVNPs) from the halophilic archaeon Halobacterium sp. NRC-1 were bioengineered to displa...

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Bibliographische Detailangaben
Veröffentlicht in:Vaccine
Hauptverfasser: DasSarma, Priya, Negi, Vidya Devi, Balakrishnan, Arjun, Karan, Ram, Barnes, Susan, Ekulona, Folasade, Chakravortty, Dipshikha, DasSarma, Shiladitya
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729386/
https://ncbi.nlm.nih.gov/pubmed/24950351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.06.021
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