Haloarchaeal gas vesicle nanoparticles displaying Salmonella SopB antigen reduce bacterial burden when administered with live attenuated bacteria

Innovative vaccines against typhoid and other Salmonella diseases that are safe, effective, and inexpensive are urgently needed. In order to address this need, buoyant, self-adjuvating gas vesicle nanoparticles (GVNPs) from the halophilic archaeon Halobacterium sp. NRC-1 were bioengineered to displa...

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Dettagli Bibliografici
Pubblicato in:Vaccine
Autori principali: DasSarma, Priya, Negi, Vidya Devi, Balakrishnan, Arjun, Karan, Ram, Barnes, Susan, Ekulona, Folasade, Chakravortty, Dipshikha, DasSarma, Shiladitya
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729386/
https://ncbi.nlm.nih.gov/pubmed/24950351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.06.021
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