Haloarchaeal gas vesicle nanoparticles displaying Salmonella SopB antigen reduce bacterial burden when administered with live attenuated bacteria

Innovative vaccines against typhoid and other Salmonella diseases that are safe, effective, and inexpensive are urgently needed. In order to address this need, buoyant, self-adjuvating gas vesicle nanoparticles (GVNPs) from the halophilic archaeon Halobacterium sp. NRC-1 were bioengineered to displa...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: DasSarma, Priya, Negi, Vidya Devi, Balakrishnan, Arjun, Karan, Ram, Barnes, Susan, Ekulona, Folasade, Chakravortty, Dipshikha, DasSarma, Shiladitya
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729386/
https://ncbi.nlm.nih.gov/pubmed/24950351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.06.021
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