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Isoform prefiltering improves performance of count-based methods for analysis of differential transcript usage
BACKGROUND: RNA-seq has been a boon to the quantitative analysis of transcriptomes. A notable application is the detection of changes in transcript usage between experimental conditions. For example, discovery of pathological alternative splicing may allow the development of new treatments or better...
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| Gepubliceerd in: | Genome Biol |
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| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4729156/ https://ncbi.nlm.nih.gov/pubmed/26813113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0862-3 |
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