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Translational development of difluoromethylornithine (DFMO) for the treatment of neuroblastoma

Neuroblastoma is a childhood tumor in which MYC oncogenes are commonly activated to drive tumor progression. Survival for children with high-risk neuroblastoma remains poor despite treatment that incorporates high-dose chemotherapy, stem cell support, surgery, radiation therapy and immunotherapy. Mo...

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Detalhes bibliográficos
Publicado no:Transl Pediatr
Main Authors: Bassiri, Hamid, Benavides, Adriana, Haber, Michelle, Gilmour, Susan K., Norris, Murray D., Hogarty, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729051/
https://ncbi.nlm.nih.gov/pubmed/26835380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2224-4336.2015.04.06
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