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Stress Response Leading to Resistance in Glioblastoma—The Need for Innovative Radiotherapy (iRT) Concepts

Glioblastoma (GBM) is the most common and most aggressive malignant primary brain tumor in adults. In spite of multimodal therapy concepts, consisting of surgery, radiotherapy and chemotherapy, the median survival, merely 15–18 months, is still poor. Mechanisms for resistance of GBM to radio(chemo)t...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Combs, Stephanie E., Schmid, Thomas E., Vaupel, Peter, Multhoff, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728462/
https://ncbi.nlm.nih.gov/pubmed/26771644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers8010015
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