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Mindbomb 2 is dispensable for embryonic development and Notch signalling in zebrafish

The Mindbomb E3 ubiquitin protein ligase (Mib) family of proteins, Mib1 and Mib2, are RING finger ubiquitin ligases that share specific substrates. Mib1 is known to play essential roles in Notch signalling by ubiquitinating Notch ligands in vivo. Conversely, the functions of Mib2 in vivo are not ful...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Mikami, Shohei, Nakaura, Mizuki, Kawahara, Atsuo, Mizoguchi, Takamasa, Itoh, Motoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728363/
https://ncbi.nlm.nih.gov/pubmed/26519518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.014225
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