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Targeting of ribosomal protein S6 to dendritic spines by in vivo high frequency stimulation to induce long-term potentiation in the dentate gyrus

Late phase long-term potentiation (L-LTP) in the hippocampus is believed to be the cellular basis of long-term memory. Protein synthesis is required for persistent forms of synaptic plasticity, including L-LTP. Neural activity is thought to enhance local protein synthesis in dendrites, and one of th...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Nihonmatsu, Itsuko, Ohkawa, Noriaki, Saitoh, Yoshito, Inokuchi, Kaoru
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728348/
https://ncbi.nlm.nih.gov/pubmed/26432888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.013243
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