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Stable atrogin-1 (Fbxo32) and MuRF1 (Trim63) gene expression is involved in the protective mechanism in soleus muscle of hibernating Daurian ground squirrels (Spermophilus dauricus)

Understanding the mechanisms that protect against or limit muscle atrophy in hibernators during prolonged inactivity has important implications for its treatment. We examined whether external factors influence the pathways regulating protein synthesis and degradation, leading to muscle atrophy preve...

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Dettagli Bibliografici
Pubblicato in:Biol Open
Autori principali: Dang, Kai, Li, Ya-Zhao, Gong, Ling-Chen, Xue, Wei, Wang, Hui-Ping, Goswami, Nandu, Gao, Yun-Fang
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728309/
https://ncbi.nlm.nih.gov/pubmed/26740574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.015776
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