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Rac1 controls epithelial tube length through the apical secretion and polarity pathways

The morphometric parameters of epithelial tubes are critical to the physiology and homeostasis of most organs. In addition, many human diseases are associated with tube-size defects. Here, we show that Rac1 limits epithelial tube elongation in the developing fly trachea by promoting Rab5-dependent e...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Sollier, Kévin, Gaudé, Helori-Mael, Chartier, François J.-M., Laprise, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728308/
https://ncbi.nlm.nih.gov/pubmed/26700724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.015727
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