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HBV DNA vaccine with adjuvant cytokines induced specific immune responses against HBV infection

AIM: To seek for an effective method to improve the immune responses induced by DNA vaccine expressing HBV surface antigen (pCR3.1-S) in Balb/c mice (H-2(d)). METHODS: The pCR3.1-S plasmid and the eukaryotic expression vectors expressing murine IL-2 (pDOR-IL-2) or IL-12 (pWRG3169) were injected into...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Du, De-Wei, Jia, Zhan-Sheng, Li, Guang-Yu, Zhou, Yong-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728221/
https://ncbi.nlm.nih.gov/pubmed/12508362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v9.i1.108
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