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The REST remodeling complex protects genomic integrity during embryonic neurogenesis
The timely transition from neural progenitor to post-mitotic neuron requires down-regulation and loss of the neuronal transcriptional repressor, REST. Here, we have used mice containing a gene trap in the Rest gene, eliminating transcription from all coding exons, to remove REST prematurely from neu...
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Publicado no: | eLife |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
eLife Sciences Publications, Ltd
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4728133/ https://ncbi.nlm.nih.gov/pubmed/26745185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09584 |
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