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The REST remodeling complex protects genomic integrity during embryonic neurogenesis

The timely transition from neural progenitor to post-mitotic neuron requires down-regulation and loss of the neuronal transcriptional repressor, REST. Here, we have used mice containing a gene trap in the Rest gene, eliminating transcription from all coding exons, to remove REST prematurely from neu...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Nechiporuk, Tamilla, McGann, James, Mullendorff, Karin, Hsieh, Jenny, Wurst, Wolfgang, Floss, Thomas, Mandel, Gail
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728133/
https://ncbi.nlm.nih.gov/pubmed/26745185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09584
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