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Resolving dual binding conformations of cellulosome cohesin-dockerin complexes using single-molecule force spectroscopy
Receptor-ligand pairs are ordinarily thought to interact through a lock and key mechanism, where a unique molecular conformation is formed upon binding. Contrary to this paradigm, cellulosomal cohesin-dockerin (Coh-Doc) pairs are believed to interact through redundant dual binding modes consisting o...
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| Veröffentlicht in: | eLife |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4728124/ https://ncbi.nlm.nih.gov/pubmed/26519733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10319 |
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