Discrete spatial organization of TGFβ receptors couples receptor multimerization and signaling to cellular tension

Cell surface receptors are central to the cell's ability to generate coordinated responses to the multitude of biochemical and physical cues in the microenvironment. However, the mechanisms by which receptors enable this concerted cellular response remain unclear. To investigate the effect of c...

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Udgivet i:eLife
Main Authors: Rys, Joanna P, DuFort, Christopher C, Monteiro, David A, Baird, Michelle A, Oses-Prieto, Juan A, Chand, Shreya, Burlingame, Alma L, Davidson, Michael W, Alliston, Tamara N
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2015
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728123/
https://ncbi.nlm.nih.gov/pubmed/26652004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09300
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