OPIOID ANALGESICS AND THE RISK OF SERIOUS INFECTIONS AMONG PATIENTS WITH RHEUMATOID ARTHRITIS: A SELF-CONTROLLED CASE SERIES STUDY

OBJECTIVE: Animal and in vitro studies suggest that certain opioid analgesics impair crucial immune functions. We sought to determine if opioid use is associated with an increased risk of serious infections in patients with rheumatoid arthritis (RA). METHODS: We conducted a self-controlled case seri...

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Bibliographic Details
Published in:Arthritis Rheumatol
Main Authors: Wiese, Andrew D., Griffin, Marie R., Stein, C. Michael, Mitchel, Edward F., Grijalva, Carlos G.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728045/
https://ncbi.nlm.nih.gov/pubmed/26473742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39462
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