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Yeast and mammalian metallothioneins functionally substitute for yeast copper-zinc superoxide dismutase.

Copper-zinc superoxide dismutase catalyzes the disproportionation of superoxide anion to hydrogen peroxide and dioxygen and is thought to play an important role in protecting cells from oxygen toxicity. Saccharomyces cerevisiae strains lacking copper-zinc superoxide dismutase, which is encoded by th...

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Bibliographic Details
Main Authors: Tamai, K T, Gralla, E B, Ellerby, L M, Valentine, J S, Thiele, D J
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC47278/
https://ncbi.nlm.nih.gov/pubmed/8367458
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