P2Y12 antagonist attenuates eosinophilic inflammation and airway hyperresponsiveness in a mouse model of asthma

Leukotriene E4 (LTE4) that plays a key role in airway inflammation is expressed on platelets and eosinophils. We investigated whether blocking of the P2Y12 receptor can suppress eosinophilic inflammation in a mouse model of asthma because platelets and eosinophils share this receptor to be activated...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Cell Mol Med
Hlavní autoři: Suh, Dong‐Hyeon, Trinh, Hoang Kim Tu, Liu, Jing‐Nan, Pham, Le Duy, Park, Sang Myun, Park, Hae‐Sim, Shin, Yoo Seob
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727565/
https://ncbi.nlm.nih.gov/pubmed/26612496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12727
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky