MicroRNA-497 inhibits cell proliferation, migration, and invasion by targeting AMOT in human osteosarcoma cells

MicroRNAs (miRNAs) have a role in the development and progression of human malignancy. The expression of miR-497 is decreased in malignant tumors, which suggests a role for miR-497 as a tumor suppressor. Angiomotin is encoded by the AMOT gene, which is a target for miR-497. Angiomotin has a role in...

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Ruan, Wen-Dong, Wang, Pei, Feng, Shiqing, Xue, Yuan, Zhang, Bin
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2016
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727508/
https://ncbi.nlm.nih.gov/pubmed/26855583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S95204
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