Molecular targeted photoimmunotherapy for HER2-positive human gastric cancer in combination with chemotherapy results in improved treatment outcomes through different cytotoxic mechanisms

BACKGROUND: Photoimmunotherapy (PIT) is a novel type of molecular optical imaging-guided cancer phototherapy based on a monoclonal antibody conjugated to a photosensitizer, IR700, in combination with near-infrared (NIR) light. PIT rapidly causes target-specific cell death by inducing cell membrane d...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Ito, Kimihiro, Mitsunaga, Makoto, Arihiro, Seiji, Saruta, Masayuki, Matsuoka, Mika, Kobayashi, Hisataka, Tajiri, Hisao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727331/
https://ncbi.nlm.nih.gov/pubmed/26810644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2072-0
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