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Systematic screening of soluble expression of antibody fragments in the cytoplasm of E. coli
BACKGROUND: Disulfide bonds are the most common structural, post-translational modification found in proteins. Antibodies contain up to 25 disulfide bonds depending on type, with scFv fragments containing two disulfides and Fab fragments containing five or six disulfide bonds. The production of anti...
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| Vydáno v: | Microb Cell Fact |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4727284/ https://ncbi.nlm.nih.gov/pubmed/26809624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0419-5 |
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