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siRNA-mediated downregulation of GluN2B in the rostral anterior cingulate cortex attenuates mechanical allodynia and thermal hyperalgesia in a rat model of pain associated with bone cancer

It has previously been suggested that the upregulation of GluN2B-containing N-methyl D-aspartate receptors (GluN2B) within the rostral anterior cingulate cortex (rACC) may contribute to the development of chronic pain. The present study used a rat model of bone cancer pain in order to investigate wh...

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Bibliografiska uppgifter
I publikationen:Exp Ther Med
Huvudupphovsmän: XU, YONGGUANG, WANG, GONGMING, ZOU, XULI, YANG, ZAIQI, WANG, QIN, FENG, HAO, ZHANG, MENGYUAN
Materialtyp: Artigo
Språk:Inglês
Publicerad: D.A. Spandidos 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726859/
https://ncbi.nlm.nih.gov/pubmed/26889244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2015.2859
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