Comparative proteomics reveals abnormal binding of ATGL and dysferlin on lipid droplets from pressure overload-induced dysfunctional rat hearts

Excessive retention of neutral lipids in cardiac lipid droplets (LDs) is a common observation in cardiomyopathy. Thus, the systematic investigation of the cardiac LD proteome will help to dissect the underlying mechanisms linking cardiac steatosis and myocardial dysfunction. Here, after isolation of...

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Published in:Sci Rep
Main Authors: Li, Linghai, Zhang, Huina, Wang, Weiyi, Hong, Yun, Wang, Jifeng, Zhang, Shuyan, Xu, Shimeng, Shu, Qingbo, Li, Juanfen, Yang, Fuquan, Zheng, Min, Qian, Zongjie, Liu, Pingsheng
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726412/
https://ncbi.nlm.nih.gov/pubmed/26795240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19782
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