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Somatic Copy Number Alterations at Oncogenic Loci Show Diverse Correlations with Gene Expression

Somatic copy number alterations (SCNAs) affecting oncogenic drivers have a firmly established role in promoting cancer. However, no agreed-upon standard exists for calling locus-specific amplifications and deletions in each patient sample. Here, we report the correlative analysis of copy number ampl...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Roszik, Jason, Wu, Chang-Jiun, Siroy, Alan E., Lazar, Alexander J., Davies, Michael A, Woodman, Scott E, Kwong, Lawrence N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726397/
https://ncbi.nlm.nih.gov/pubmed/26787600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19649
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