IFNα enhances the production of IL-6 by human neutrophils activated via TLR8

Recently, we reported that human neutrophils produce biologically active amounts of IL-6 when incubated with agonists activating TLR8, a receptor recognizing viral single strand RNA. In this study, we demonstrate that IFNα, a cytokine that modulates the early innate immune responses toward viral and...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Zimmermann, Maili, Arruda-Silva, Fabio, Bianchetto-Aguilera, Francisco, Finotti, Giulia, Calzetti, Federica, Scapini, Patrizia, Lunardi, Claudio, Cassatella, Marco A., Tamassia, Nicola
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726390/
https://ncbi.nlm.nih.gov/pubmed/26790609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19674
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