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Lactate Chemical Exchange Saturation Transfer (LATEST) Imaging in vivo A Biomarker for LDH Activity

Non-invasive imaging of lactate is of enormous significance in cancer and metabolic disorders where glycolysis dominates. Here, for the first time, we describe a chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) method (LATEST), based on the exchange between lactate hydro...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: DeBrosse, Catherine, Nanga, Ravi Prakash Reddy, Bagga, Puneet, Nath, Kavindra, Haris, Mohammad, Marincola, Francesco, Schnall, Mitchell D., Hariharan, Hari, Reddy, Ravinder
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726389/
https://ncbi.nlm.nih.gov/pubmed/26794265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19517
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