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Identification of novel noncoding transcripts in telomerase-negative yeast using RNA-seq

Telomerase is a ribonucleoprotein that maintains the ends of linear chromosomes in most eukaryotes. Loss of telomerase activity results in shortening of telomeric DNA and eventually a specific G2/M cell-cycle arrest known as senescence. In humans, telomere shortening occurs during aging, while inapp...

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Udgivet i:Sci Rep
Main Authors: Niederer, Rachel O., Papadopoulos, Nickolas, Zappulla, David C.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726298/
https://ncbi.nlm.nih.gov/pubmed/26786024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19376
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