AMPK Suppresses Connexin43 Expression in the Bladder and Ameliorates Voiding Dysfunction in Cyclophosphamide-induced Mouse Cystitis

Bladder voiding dysfunction is closely related to local oxidation, inflammation, and enhanced channel activities. Given that the AMP-activated protein kinase (AMPK) has anti-oxidative, anti-inflammatory and channel-inhibiting properties, we examined whether and how AMPK affected bladder activity. AM...

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Vydáno v:Sci Rep
Hlavní autoři: Zhang, Xiling, Yao, Jian, Gao, Kun, Chi, Yuan, Mitsui, Takahiko, Ihara, Tatsuya, Sawada, Norifumi, Kamiyama, Manabu, Fan, Jianglin, Takeda, Masayuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726257/
https://ncbi.nlm.nih.gov/pubmed/26806558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19708
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