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Peptides in headlock – a novel high-affinity and versatile peptide-binding nanobody for proteomics and microscopy
Nanobodies are highly valuable tools for numerous bioanalytical and biotechnical applications. Here, we report the characterization of a nanobody that binds a short peptide epitope with extraordinary affinity. Structural analysis reveals an unusual binding mode where the extended peptide becomes par...
Enregistré dans:
| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4726124/ https://ncbi.nlm.nih.gov/pubmed/26791954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19211 |
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