Lipoprotein hydrophobic core lipids are partially extruded to surface in smaller HDL: “Herniated” HDL, a common feature in diabetes

Recent studies have shown that pharmacological increases in HDL cholesterol concentrations do not necessarily translate into clinical benefits for patients, raising concerns about its predictive value for cardiovascular events. Here we hypothesize that the size-modulated lipid distribution within HD...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Amigó, Núria, Mallol, Roger, Heras, Mercedes, Martínez-Hervás, Sergio, Blanco-Vaca, Francisco, Escolà-Gil, Joan Carles, Plana, Núria, Yanes, Óscar, Masana, Lluís, Correig, Xavier
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726105/
https://ncbi.nlm.nih.gov/pubmed/26778677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19249
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