The Epstein-Barr virus encoded LMP1 oncoprotein modulates cell adhesion via regulation of activin A/TGFβ and β1 integrin signalling

Approximately 20% of global cancer incidence is causally linked to an infectious agent. Epstein-Barr virus (EBV) accounts for around 1% of all virus-associated cancers and is associated with nasopharyngeal carcinoma (NPC). Latent membrane protein 1 (LMP1), the major oncoprotein encoded by EBV, behav...

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Udgivet i:Sci Rep
Main Authors: Morris, Mhairi A., Dawson, Christopher W., Laverick, Louise, Davis, Alexandra M., Dudman, Joe P. R., Raveenthiraraj, Sathuwarman, Ahmad, Zeeshan, Yap, Lee-Fah, Young, Lawrence S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726061/
https://ncbi.nlm.nih.gov/pubmed/26782058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19533
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