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Gel electrophoresis in a polyvinylalcohol coated fused silica capillary for purity assessment of modified and secondary-structured oligo- and polyribonucleotides

Application of a polyvinylalcohol-coated (PVA-coated) capillary in capillary gel electrophoresis (CGE) enables the selective separation of oligoribonucleotides and their modifications at high resolution. Quality assessment of shorter oligomers of small interfering RNA (siRNA) is of key importance fo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Barciszewska, Martyna, Sucha, Agnieszka, Bałabańska, Sandra, Chmielewski, Marcin K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726012/
https://ncbi.nlm.nih.gov/pubmed/26777121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19437
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