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Plug-and-Display: decoration of Virus-Like Particles via isopeptide bonds for modular immunization

Virus-like particles (VLPs) are non-infectious self-assembling nanoparticles, useful in medicine and nanotechnology. Their repetitive molecularly-defined architecture is attractive for engineering multivalency, notably for vaccination. However, decorating VLPs with target-antigens by genetic fusion...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Brune, Karl D., Leneghan, Darren B., Brian, Iona J., Ishizuka, Andrew S., Bachmann, Martin F., Draper, Simon J., Biswas, Sumi, Howarth, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725971/
https://ncbi.nlm.nih.gov/pubmed/26781591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19234
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