Endogenous sulfur dioxide alleviates collagen remodeling via inhibiting TGF-β/Smad pathway in vascular smooth muscle cells

The study was designed to investigate the role of endogenous sulfur dioxide (SO(2)) in collagen remodeling and its mechanisms in vascular smooth muscle cells (VSMCs). Overexpression of endogenous SO(2) synthase aspartate aminotransferase (AAT) 1 or 2 increased SO(2) levels and inhibited collagen I a...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Huang, Yaqian, Shen, Zhizhou, Chen, Qinghua, Huang, Pan, Zhang, Heng, Du, Shuxu, Geng, Bin, Zhang, Chunyu, Li, Kun, Tang, Chaoshu, Du, Junbao, Jin, Hongfang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725894/
https://ncbi.nlm.nih.gov/pubmed/26762477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19503
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